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Cell signalling / John T. Hancock

Main Author Hancock, John T. Country Reino Unido. Edition 3rd ed Publication Oxford : Oxford University Press, 2010 Description XXII, 341 p. : il. ; 25 cm ISBN 978-0-19-923210-9 CDU 576.5
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Enhanced descriptions from Syndetics:

Signalling within and between cells is an essential part of many biological processes, from the development of the body, to the activity of our immune system. Recent advances in molecular cell biology have allowed us to identify the components of signalling pathways, and examine how theyinteract to form the carefully orchestrated and controlled networks upon which the complexity of a living organism is built.Starting with an overview of cell signalling and highlighting its importance in many biological systems, the book goes on to explore the key components of extracellular and intracellular signalling mechanisms, before examining how these components come together to create signalling pathways, whichare so crucial to the survival of many living organisms.Cell Signalling presents a carefully structured introduction to this intricate subject, introducing those conserved features that underlie many different extra- and intracellular signalling systems.* A focus on generic components of extra- and intracellular signalling pathways allows the student to gain a thorough understanding of the underlying principles of cell signalling before exploring how the individual components inteeract to form complex signalling pathways* The ubiquity of key signalling mechanisms is highlighted, enabling students to see how similar mechanisms are conserved and harnessed in many different biological systems* The student is directed to carefully chosen further reading articles, allowing them to readily explore key topics in more detailThe Online Resource Centre to accompany Cell Signalling features:For students:* Links to useful websites* Hyperlinked referencesFor Lecturers:* All figures from the book

Table of contents provided by Syndetics

  • Figure Legends
  • Preface
  • Abbreviations
  • Part I An overview of cell signalling
  • 1 Aspects of cellular signalling
  • 2 Pathways are the key to signalling
  • 3 A look at some of the history and techniques of cell signalling
  • Part II Components which comprise signalling pathways
  • 4 Extracellular signals: hormones, cytokines and growth factors
  • 5 Detection of extracellular signals: the role of receptors
  • 6 Protein Phosphorylation, kinases and phosphatases
  • 7 Cyclic nucleotides, cyclases and G proteins
  • 8 Inositol phosphate metabolism and roles of membrane lipids
  • 9 Intracellular calcium: Its control and role as an intracellular signal
  • 10 Reactive oxygen species, reactive nitrogen species and redox signalling
  • Part III Selected examples of signalling pathways and events
  • 11 Insulin and the signal transduction cascades it invokes
  • 12 Perception of the environment
  • 13 Signalling in development and for the regulation of gene expression
  • 14 Life, death and apoptosis
  • Part IV Final thoughts
  • 15 Cell Signalling: importance, complexity, and future
  • Index

Author notes provided by Syndetics

Dr John Hancock is Reader in Molecular Biology in the Faculty of Applied Science at the University of the West of England, Bristol, UK.

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