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Fundamentals of enzyme kinetics / Athel Cornish-Bowden

Main Author Cornish-Bowden, Athel, 1943- Country Reino Unido. Edition Rev. ed. Publication London : Portland Press, cop. 1995 Description XIII, 343 p. : il. ; 25 cm ISBN 1-85578-072-0 CDU 577.1 577.15

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Item type	Current location	Call number	Status	Date due	Barcode	Item holds	Course reserves
Monografia	Biblioteca Geral da Universidade do Minho	BGUM 577.1 - C	Available		240499		Licenciatura em Bioquímica Enzimologia 1º semestre

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Enhanced descriptions from Syndetics:

Since the first edition was published in 1979, the development of techniques for studying and manipulating genes have transformed biochemistry. Nonetheless, enzymes remain at the heart of all living systems, and an understanding of how they operate is vital for understanding the chemistry of life. This book describes the principles of enzyme kinetics, with an emphasis on principles rather than an encyclopaedic accumulation of facts, to allow readers to fill gaps for themselves and proceed in the subject as far as they need to go. In this way it provides the basis for understanding enzyme kinetics, whether at the level of the undergraduate, the research student or the researcher.

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CHOICE Review

Cornish-Bowden, a renowned expert in the field of enzyme kinetics, focuses on the purely kinetic behavior of enzymes and provides little, if any, details about enzyme structure. In this new edition (1st ed., 1979), basic kinetic concepts (as applied to all chemical reactions) are reviewed, followed by a review of Michaelis-Menten enzyme kinetics, catalytic RNA, and catalytic antibodies. The author describes aspects of kinetic studies, such as the proper use of isotopes and the effect of the environment (pH dependence, for example) on enzyme activity. He provides an extensive discussion of how to interpret data from such experiments. Readers should be familiar with calculus and linear algebra, as the mathematical discussions are quite rigorous. More complex enzyme systems are described, such as allosteric enzymes and multienzyme systems. About a half-dozen or so problems can be found at the end of each chapter, and solutions to the problems are provided in an appendix. More than 300 references. Graduate. K. Cornely; Providence College